美国艾伯特爱因斯坦医学院招聘分子药理学、生理学博士后、访问学者,要求申请者有分子生物学/生理学/电生理学/同源建模等方面的知识背景,博士学习期间有大量的研究成果。
Postdoctoral Fellow, Molecular Pharmacology/Physiology
Structure-Function, Molecular Genetics of the
Proton-Coupled Folate/Antifolate Transporter
A postdoctoral position is available for studies on the structure-function, molecular genetics, and biological/pharmacological properties of the proton-coupled folate transporter (PCFT) cloned by this laboratory (Cell 127:917-928, 2006). Loss-of-function mutations in his transporter are the molecular basis of hereditary folate malabsorption. PCFT mediates intestinal folate absorption, folate transport across the choroid plexus and transport of antifolates into tumor cells within their acidic microenvironment. Candidates should have a strong background in molecular biology and/or physiology/electrophysiology/ homology modeling and a track-record of productivity during their doctoral training. This is a participating laboratory in the Experimental Therapeutics Program of the NCI-designated Albert Einstein Cancer Center.